February, 2003
© 2000, 2001, 2003 Scott S. Emerson, M.D., Ph.D.
Session 1- Fixed Sample Design: 93
Case Study: Scientific Hypotheses
Background
Critically ill patients often get overwhelming bacterial infection (sepsis), after which mortality is high
Gram negative sepsis often characterized by production of endotoxin, which is thought to be the cause of much of the ill effects of gram negative sepsis
Hypothesize that administering antibody to endotoxin may decrease morbidity and mortality