February, 2003
© 2000, 2001, 2003 Scott S. Emerson, M.D., Ph.D.
Session 1- Fixed Sample Design: 98
Case Study: Logistical Considerations
Logistical considerations with relevance to statistical design
Multicenter clinical trial
·Long term follow-up difficult in trauma centers
·Data management is complicated
·
Exclusion criteria to reflect study setting
·exclude noncompliant patients
·try to increase statistical precision