February, 2003
© 2000, 2001, 2003 Scott S. Emerson, M.D., Ph.D.
Session 1-
Fixed Sample Design: 112
Case Study: Statistical Design Issues
Determining the sample size (cont.)
General sample size formula:
·d
= standardized alternative
·D = difference between null and alternative treatment effects
·V = variability of sampling unit
·n = number of sampling units
