February, 2003
© 2000, 2001, 2003 Scott S. Emerson, M.D., Ph.D.
Session 1- Fixed Sample Design: 120
S+SeqTrial
Evaluating the fixed sample study
Frequentist inference at the boundaries
Inferences at the Boundaries
                    *** a Boundary *** *** d Boundary ***
Time 1     Boundary             -0.035             -0.035
                MLE             -0.035             -0.035
            P-value              0.025              0.025
       95% Conf Int         (-0.07, 0)         (-0.07, 0)