February, 2003
© 2000, 2001, 2003 Scott S. Emerson, M.D., Ph.D.
Session 1- Fixed Sample Design: 117
Case Study: Statistical Design Issues
Evaluating the operating characteristics (cont.)
Confidence interval at the critical value
·Observed value which fails to reject null
·Set of hypothesized treatment effects which might reasonably generate data like that observed
-Have we excluded all scientifically meaningful alternatives with a negative study?
-(Basic science relevance)