February, 2003
© 2000, 2001, 2003 Scott S. Emerson, M.D., Ph.D.
Issues (cont.)
Scientific
·How to
define scientific hypotheses when trying to establish
-efficacy by
comparing a new treatment to no treatment
-efficacy by
comparing a new treatment to an existing efficacious treatment
-superiority
of one treatment over another
·How to
choose the comparison group when trying to establish efficacy
by comparing a new treatment to an existing efficacious
treatment