February, 2003
© 2000, 2001, 2003 Scott S. Emerson, M.D., Ph.D.
Session 1- Fixed Sample Design: 58
Decision Theoretic Approach: Tests
We can describe clinical trial designs that discriminate between two or more hypotheses
One sided hypothesis tests
·Tests for superiority
·Tests for inferiority
·Shifted tests for noninferiority (one-sided equivalence)
Two sided hypothesis tests
·Tests for superiority/inferiority
·Two sided equivalence tests (e.g., bioequivalence)