February, 2003
© 2000, 2001  Scott S. Emerson, M.D., Ph.D.
Session 2: 17
Criteria for Stopping a Trial
Statistical basis for stopping criteria (cont.)
Bayesian analysis
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·Compute the probability that the treatment effect is in some specified range
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·Calculations based on a user specified prior distribution for the treatment effect (which is treated as a random variable)