February, 2003
© 2000, 2001
Scott S. Emerson, M.D., Ph.D.
Session 2: 109
Error Spending Family
Lan and DeMets (1983)
approach (cont.)
Kim and
DeMets (1987) and Jennison and Turnbull (1989) consider an error
spending family corresponding to
Useful special cases
identified by those authors:
·P = 1 is
similar to Pocock (1977)
·P = 3 is
similar to O’Brien and Fleming (1979)
