February, 2003
© 2000, 2001  Scott S. Emerson, M.D., Ph.D.
Session 2: 125
Comparison of Parameterizations
Is there a problem?
Parameterization of stopping rule families induces a grouping of designs:
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·Unified family: Pocock (1977) designs, O’Brien-Fleming (1979) designs, Triangular designs (Whitehead & Stratton, 1983)
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·Error spending families: All designs that spend the same proportion of type I or II error at each analysis