February, 2003
© 2000, 2001 Scott S. Emerson, M.D., Ph.D.
Example: Stopping
rule chosen at design
Test of normal
mean:
·Null: m £ 0.0
·Alternative:
m ³ 0.5
One-sided symmetric
test
·Size .025,
Power .975
·Four equally
spaced analyses
·Pocock
(1977) boundary relationships