February, 2003
© 2000, 2001 Scott S. Emerson, M.D., Ph.D.
Example:
Comparison with error spending approach using interpolated error spending
function
The
stopping boundary based on the error spending function will not agree
exactly with the curve for the original design, because the
error spending function is not linear for this design.
Had the
monitoring occurred at the prespecified time, the two curves would
agree.