February, 2003
© 2000, 2001 Scott S. Emerson, M.D., Ph.D.
Session 3: 56
Measuring Study Time
Example: Superposed stopping rules from first and second interim analyses using unified family
Because the monitoring bounds were constrained on the sample mean scale, the stopping boundaries computed for the first analysis agree at both analyses when plotted on the sample mean scale
If the boundaries were plotted on some other scale, they would not agree