Analyses Adjusted for
Stopping Rules
Reporting
Results
Adjustment for
Stopping Rules
Choice of Inferential
Methods
Methods of Point
Estimation
Orderings of the
Outcome Space
Relative
Advantages
Sensitivity to Poorly
Specified Stopping Rules
Case Study I: Absence
of Formal Stopping Rule
Case Study II:
Unexpected Toxicities
Documentation of
Design, Monitoring and Analysis