February, 2003
© 2000 Scott S. Emerson, M.D., Ph.D.
Session
4:
27
Methods of Point Estimation
Point estimates adjusted for stopping rule
Bias adjusted mean (Whitehead, 1986)
·
Assume observed outcome is mean of true
distribution
·
Requires knowing number and timing of future
analyses
·
Generally still biased
·
Often least mean squared error