February, 2003
© 2000 Scott S. Emerson, M.D., Ph.D.
Session 4: 28
Methods of Point Estimation
Point estimates adjusted for stopping rule
Median unbiased estimate (Whitehead, 1984)
·Assume observed outcome is median of true distribution
·Requires an ordering of the outcome space
·Some orderings require knowledge of number and timing of future analyses
·Generally still biased for mean