February, 2003
© 2000 Scott S. Emerson, M.D., Ph.D.
Session 4: 94
Final comments
Hybrid rule could have been more complicated to account for later decisions to switch
Sensitivity analysis suggests appropriate inference in this case (could use as a criterion for GST)
Adjusted inference possible, but more complex
Bayesian analysis of some interest, but it is questionable that a proper prior could ever be selected to detect unexpected toxicities