February, 2003
© 2000, 2001, 2003 Scott S. Emerson, M.D., Ph.D.
Frequentist Methods 1: 17
Statistical Issues
The confidence interval associated with an observed test statistic is found by integrating the sampling density under all hypotheses.
A particular hypothesized treatment effect is in a 100(1-a)% confidence interval for the observation if, based on the sampling density for that hypothesis, the probability of a test statistic lower (or greater) than the observed value is between a/2 and 1-a/2
(For which hypothesized values of the treatment effect is the observed data not too unusual?)