February, 2003
© 2000, 2001, 2003 Scott S. Emerson, M.D., Ph.D.
Frequentist Methods 1: 20
Statistical Issues
Many point estimates of the true treatment effect are based on the sampling density.
Find the value of the treatment effect for which the observed test statistic is
·the mean of its sampling distribution
·the median of its sampling distribution
·the mode of its sampling distribution
·
Maximum likelihood estimates correspond to finding the value of the treatment effect for which the sampling density of the observed data is maximized. (Need to consider sufficiency of statistics.)