February, 2003
© 2000, 2001, 2003 Scott S. Emerson, M.D., Ph.D.
Phases of Clinical Trials:
8
Impact on Study Design
The stage of clinical investigation is a major factor
to consider in choosing a particular clinical trial
design
Scientific issues
·
Strength of evidence
required at the end of the
trial
·
Ethical issues
·
Potential for benefit (or harm) to patients
·