February, 2003
© 2000, 2001, 2003 Scott S. Emerson, M.D., Ph.D.
Screening Studies: 16
Preliminary Studies in Screening
Comparison of scenarios
Scenario 1: Only large trials
·Use 1,000,000 subjects
·Screen 1,000 new treatments
·Adopt 98 effective treatments
·Adopt 45 ineffective treatments
Scenario 2: Use of pilot studies
·Use 999,500 subjects
·Screen 12,500 new treatments
·Adopt 150 effective treatments
·Adopt 28 ineffective treatments