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Causation vs Association
Truly determining causation requires a suitable interventional study (experiment)
–Statistical analyses tell us about associations
–Associations in the presence of an appropriate experimental design allows us to infer causation
•But even then, we need to be circumspect in identifying the true mechanistic cause
»E.g., a treatment that causes headaches, and therefore aspirin use, may result in lower heart attack rates due entirely to the use of aspirin