ptid tx age sex weight height durdis stage splen bili alb alkphos alt ptsec chol plt dlcoBsln dlcoFnl dlcoMin stopdrug reason obsprog progress obsdeath death 1 0 60 0 79.4 154.21 244 4 1 0.7 3.9 598 61 9.7 284 249 14.6 NA NA 395 cancer 858 1 858 1 2 1 54 0 57.1 155.8 290 1 1 0.7 3.9 215 21 12.2 248 408 23.5 15.9 15.1 2631 DSMB 3003 0 3003 0 3 1 56 0 74.3 153.1 1047 3 1 0.8 3.7 409 108 NA 262 170 23 19.8 18.6 2170 progression 2170 1 2353 0 4 0 53 0 61.8 156.3 273 2 1 0.2 3.9 292 51 11.6 220 331 24.4 18.8 19 2495 DSMB 2834 0 2834 0 5 0 57 0 66.3 159.4 4919 4 1 0.7 3.6 81 16 11.6 246 264 12.5 9 8.9 2700 DSMB 3107 0 3107 0 6 0 47 0 77.6 168.9 1962 3 1 0.7 4.4 73 29 13.1 230 195 26.4 19 19 3104 DSMB 3452 0 3452 0 7 0 57 0 64.4 165.9 636 2 1 0.4 4 203 32 10.4 201 241 17.8 21.4 14.2 3209 DSMB 3640 0 3640 0 8 1 48 0 59.8 157.8 324 3 1 0.4 3.9 149 29 12.9 178 239 15.4 14 13.7 2897 DSMB 3282 0 3282 0 9 1 45 0 70.1 163.19 1149 3 2 0.5 3.7 219 27 9.4 225 169 26 20.7 16.5 2999 DSMB 3443 0 3443 0 10 1 53 0 52.1 158.69 306 2 1 0.7 3.9 158 38 11.4 270 430 17.2 15.8 15.5 2621 DSMB 2988 0 2988 0 11 0 41 0 88.7 160.7 1305 2 1 0.5 4.4 82 74 11.9 185 166 22.5 22.2 20.3 3048 DSMB 3415 0 3415 0 12 1 55 0 59.3 161.9 1333 3 1 0.7 4 301 87 12.1 316 278 19.5 18.4 16 1026 cancer 2584 1 3404 0 13 1 46 0 75.4 158.89 2505 2 1 0.1 3.8 246 38 10.5 266 291 16.8 20 16.6 2671 DSMB 2996 0 2996 0 14 1 53 0 87.1 171.71 350 1 2 0.2 4.2 181 31 11 194 270 22 19.9 18.9 2931 DSMB 3339 0 3339 0 15 1 40 0 55.2 161.9 2103 3 1 0.6 3.6 930 190 8.8 353 320 16.5 19.5 19 1921 DSMB 2351 0 2351 0 16 0 46 0 55.5 164.6 2264 3 1 1.1 3.9 223 122 10.9 199 137 19.5 18.6 14.2 3041 DSMB 3451 0 3451 0 17 1 44 0 107.8 166.3 1625 2 1 0.7 4.1 158 51 12.1 279 364 16.5 8.7 6.8 2999 DSMB 3385 0 3385 0 18 0 48 0 78.5 160.7 280 1 1 0.5 4 153 36 12 194 304 26.7 21.7 21.7 2278 DSMB 2731 0 2731 0 19 0 55 0 60.8 156.3 3688 4 1 0.6 4.1 352 81 11.1 373 185 17.1 14.8 15 2103 progression 1427 1 2187 1 20 1 44 0 80.6 164 386 2 1 0.3 3.8 127 31 NA 190 289 21.1 18.5 14.3 2355 DSMB 2727 0 2727 0 21 1 49 0 43.6 151.1 1246 2 1 0.6 3.8 224 87 NA NA 168 24.2 19.5 18 2992 DSMB 3431 0 3431 0 22 0 55 0 81.6 166.24 1327 3 1 0.4 4 319 61 10.5 212 289 23.4 21.9 21.7 1949 DSMB 2321 0 2321 0 23 0 64 0 89 166.5 2183 2 1 0.6 3.7 109 20 9.6 214 250 15.3 13.8 13.8 2005 DSMB 2449 0 2449 0 24 1 50 0 65.7 162.7 2025 3 1 2.3 3.9 395 64 11.8 259 119 19.1 18.6 18.4 530 progression 590 1 833 0 25 0 57 0 55 159.9 756 3 1 1.4 4.2 601 97 12.3 290 171 20.7 15 15 2009 AE 2095 1 2209 0 26 0 51 0 82.7 147.7 297 3 1 0.1 4.1 123 43 9.6 236 223 16.4 19 16.9 2418 DSMB 2765 0 2765 0 27 1 68 1 72.5 173.8 248 3 1 0.7 4.3 109 17 10.9 267 229 18.2 11.1 11.1 340 AE 2698 0 2698 0 28 0 59 0 47 164.6 185 3 1 0.1 3.8 245 51 9.4 163 331 15.4 16.1 16.1 1830 DSMB 2176 0 2176 0 29 0 66 0 71.4 164.5 1545 3 1 0.5 3.4 80 24 11.9 NA 243 24.5 18.7 18.5 2315 DSMB 2668 0 2668 0 30 0 33 0 65.7 157.9 237 3 1 0.3 3.8 75 21 11.9 193 301 16.9 22.7 22.9 541 pregnancy 3233 0 3233 0 31 1 48 0 71.2 154.7 253 3 1 0.6 3.9 211 21 11.1 234 261 16.2 16.7 16.5 2279 DSMB 2713 0 2713 0 32 0 47 0 97.5 169.5 366 1 1 0.5 3.7 171 19 11.7 234 260 21.8 19.8 18.8 2251 DSMB 2596 0 2596 0 33 0 52 0 74.1 162.69 412 1 1 0.3 4 110 17 9.7 250 291 16.7 18.7 12.2 2427 DSMB 2752 0 2752 0 34 1 68 0 60.4 156.1 1786 3 1 0.5 3.8 176 43 11.9 212 169 16.5 19.2 11.6 2768 cancer 3542 0 3542 0 35 1 60 0 69.1 163.6 2327 3 1 0.6 3.7 184 17 11.1 222 127 15.8 16.1 15.8 1173 AE 3557 0 3557 0 36 0 64 0 62.2 152.8 493 2 1 0.4 4 102 27 12.7 186 215 17.4 15.8 14.4 2236 DSMB 2588 0 2588 0 37 1 33 0 69.7 163.5 1531 3 1 0.6 4 394 63 11.1 231 184 24.5 22 18.8 3195 DSMB 3605 0 3605 0 38 0 58 0 68 147.4 1092 3 1 0.4 4 524 93 8.6 322 347 13.8 10.1 9.9 1970 DSMB 2372 0 2372 0 39 0 39 0 74.4 156.1 495 3 2 1 3.5 233 48 12.3 194 186 16.4 16.2 16.2 783 progression 783 1 1721 0 40 0 42 0 64 160.4 198 2 1 0.3 3.8 1094 100 10.8 554 201 12.7 20.8 13.2 2264 AE 2426 1 2426 1 41 1 50 0 75.9 163.4 2375 3 1 0.7 4.1 223 26 10.6 218 228 19.9 15.4 15.6 1985 DSMB 2357 0 2357 0 42 0 58 0 67.04 154.9 895 4 1 0.2 4.2 326 76 8.6 288 206 15.6 NA NA 59 inconvenience 2267 0 2267 0 43 0 60 0 108.7 161.7 361 4 1 1.6 3.5 97 61 11.6 236 129 20.1 18 17.8 458 progression 158 1 530 0 44 0 25 0 85.7 176.71 253 2 1 0.9 3.4 219 137 9.4 254 333 17.6 23.1 22.5 2126 DSMB 2506 0 2506 0 45 0 59 0 69.8 166.4 1283 3 1 0.3 3.7 595 123 9.7 246 209 19.7 21.5 18.5 2166 DSMB 709 1 2177 0 46 1 31 0 87.7 162.1 764 3 1 1.5 4.3 279 105 11.1 472 304 25 15.7 15.5 2996 DSMB 2938 1 3365 0 47 0 46 0 65.3 160.1 538 1 1 1.4 3.7 79 44 11.7 198 119 16.8 16 16.2 1991 DSMB 849 1 2430 0 48 1 40 0 51.1 150.7 248 2 1 1.1 4 520 174 11.4 274 120 22.9 19.6 18.7 2674 DSMB 3098 0 3098 0 49 1 48 0 81.6 162.2 807 3 1 0.5 3.7 312 44 11.1 221 306 15 18.8 15.9 2972 DSMB 3374 0 3374 0 50 0 55 0 68 159.8 3526 3 1 0.8 4.1 446 80 11.1 222 266 16.7 14.2 14.4 3070 DSMB 3417 0 3417 0 51 0 60 0 85.1 171.7 286 2 2 0.3 3.9 189 20 10.6 167 319 28 24.7 20.9 2943 DSMB 3317 0 3317 0 52 1 66 0 96.8 168.5 1170 3 2 0.8 3.3 147 44 12.9 202 166 17.3 28.8 16.6 2195 AE 1659 1 2659 0 53 0 61 0 84.4 169 3200 4 1 1.3 4.7 145 36 12.1 293 244 20.1 17.8 17.7 2392 DSMB 2748 0 2748 0 54 0 45 0 111.1 171.3 676 2 1 0.8 3.9 183 30 12.3 227 238 24.2 19 19 1680 inconvenience 1690 0 1690 0 55 1 50 1 75.1 176.9 727 2 1 1.3 3.6 367 18 11.9 137 361 31.7 21.2 20.5 2967 DSMB 2881 1 3357 0 56 1 49 0 82.8 165.4 709 2 1 1.9 3.4 474 76 11.1 331 139 16.4 14.7 13.2 1830 progression 1507 1 2190 0 57 0 51 0 81.9 159.98 1372 2 1 0.5 4.6 120 32 11.9 204 307 24.5 15.5 14.9 3098 DSMB 3454 0 3454 0 58 0 53 0 65.5 160.6 1742 1 1 0.74 4.4 82 19 11.9 345 259 20 14.3 14.1 2874 DSMB 2958 0 2958 0 59 1 38 0 61.2 157.68 378 3 1 0.6 4.1 76 23 11.3 209 259 18.3 17.2 15.5 2061 DSMB 2452 0 2452 0 60 0 56 0 148.9 168.6 1413 2 1 0.9 3.8 243 40 11.7 292 189 22.2 14.9 15.1 2503 DSMB 2941 0 2941 0 61 0 68 0 66.5 163.3 800 2 1 0.2 4.3 161 22 10.3 265 327 16.3 16 15.1 2621 AE 3315 1 3514 0 62 1 50 0 65.42 174 2241 2 1 1.9 4.2 470 84 12.2 291 147 10 15.8 15.2 2670 DSMB 3112 0 3112 0 63 1 48 0 102.3 160 248 2 1 0.8 4.1 158 49 12.4 258 340 21.9 16.8 15.4 1852 DSMB 2297 0 2297 0 64 1 46 1 56.5 174.5 1606 3 1 0.6 3.9 121 24 11.5 211 400 23.8 28.9 24.5 2830 DSMB 3023 0 3023 0 65 1 64 0 65 153.5 202 2 1 0.3 4.2 120 24 9.3 281 316 11.6 12.9 12 2006 DSMB 2387 0 2387 0 66 1 63 0 55.2 154.6 5170 4 2 0.7 3.7 208 66 10.9 217 169 14.8 14.3 12.9 2972 DSMB 3388 0 3388 0 67 1 53 0 73.1 161.9 5652 1 1 0.6 4.2 303 34 NA 253 279 17.4 19.8 18.4 2719 DSMB 3136 0 3136 0 68 0 48 0 83.6 168 2847 2 1 0.6 3.6 143 34 13.1 128 344 22.5 18.5 17.1 2950 DSMB 3316 0 3316 0 69 1 52 0 68.4 167.3 1457 4 1 1.4 4.1 233 85 11.3 289 301 24.5 19.2 17.4 3073 DSMB 3421 0 3421 0 70 1 43 0 69.6 172.11 310 2 1 0.2 3.9 308 46 9.4 204 145 18.1 19.1 14.9 2558 DSMB 2954 0 2954 0 71 0 52 1 86.2 174.6 1783 3 1 0.6 4.1 102 68 11.4 136 143 30.6 27.4 27.2 3101 DSMB 3411 0 3411 0 72 0 56 0 68.5 157.2 3098 4 1 0.7 3.7 146 31 12.2 200 171 16.9 16.8 15.3 3112 DSMB 3489 0 3489 0 73 0 35 0 96.7 160.1 384 3 1 0.6 3.7 409 60 11.2 276 240 15.1 NA NA 39 inconvenience 49 0 49 0 74 1 43 0 58.2 174.4 1515 3 1 0.3 4.7 222 33 9.5 203 278 20.3 21.6 21.6 2006 DSMB 2448 0 2448 0 75 1 39 0 75.7 174.7 632 2 1 0.7 5.9 218 65 12.1 234 266 28.4 24.1 20.5 3132 DSMB 3478 0 3478 0 76 1 49 0 64.3 155.9 377 2 1 2 3.9 534 49 13.1 185 136 20.2 NA NA 373 inconvenience 383 0 383 0 77 0 43 0 59.8 165.4 1895 4 2 0.9 4.2 120 27 12.5 179 90 18.4 16.2 16.4 3128 DSMB 3452 0 3452 0 78 0 37 0 69.5 163.4 2031 2 2 1.2 3.6 471 87 12 271 106 28.2 NA NA 247 AE 1177 1 1177 0 79 1 69 0 53.4 151.9 344 2 1 0.9 4.3 230 18 12 212 185 12.1 12.7 12.5 2034 DSMB 2468 0 2468 0 80 0 43 1 87.3 173.9 376 3 1 0.9 3.9 222 51 11.2 208 139 20.3 20.7 20.2 2418 DSMB 2820 0 2820 0 81 1 49 0 104.9 175.3 307 3 1 0.3 3.7 128 19 11.1 219 269 17.2 18.6 18.8 2901 DSMB 3290 0 3290 0 82 1 43 0 90.7 172.6 294 3 1 0.7 4.5 226 36 12.4 261 228 22.2 22 22 809 comorbidity 2442 0 2442 0 83 0 57 0 50.1 160.6 1853 3 1 0.6 4.5 101 19 11.9 221 340 21.8 14.7 11.2 3155 DSMB 3549 0 3549 0 84 0 59 1 94.7 181.6 624 4 1 0.1 4 137 35 10.6 205 109 22.7 19.7 19.7 2482 cancer 2883 1 2883 0 85 1 55 0 71.8 174.9 218 2 1 0.8 4.2 172 35 9.8 212 224 21.9 19 18 1844 DSMB 2246 0 2246 0 86 1 44 0 84.4 156.4 3946 2 1 0.5 4.3 187 41 11.6 316 249 21.3 16.3 13.9 2174 inconvenience 2184 0 2184 0 87 1 42 0 96.6 170.3 443 3 1 0.6 3.8 106 18 11.1 182 201 22.6 22.4 19.2 1998 DSMB 2365 0 2365 0 88 0 58 0 89.6 166 591 1 1 0.3 3.9 117 21 8.9 211 240 19.2 20.7 19.8 1831 DSMB 2190 0 2190 0 89 0 60 0 57.2 153.4 3135 3 1 0.5 4 130 27 10.7 201 164 16 12.7 12.7 3019 DSMB 3452 0 3452 0 90 0 55 0 68.7 157.1 1983 4 1 0.8 4 309 44 12.1 215 145 20.8 16.8 15.8 2732 comorbidity 2996 0 2996 0 91 0 51 0 66.4 163.2 686 3 2 1 2.9 203 19 12.7 141 77 14.1 NA NA 445 inconvenience 810 1 2236 1 92 1 63 0 69 151.9 4276 3 1 0.3 3.5 317 53 10.1 238 201 14.8 13.1 13.1 1330 cancer 1330 1 3431 0 93 0 46 0 74.7 160.2 371 3 1 0.1 4 136 48 9 251 168 18.4 18.2 17.5 2104 DSMB 2548 0 2548 0 94 0 49 0 73.3 166.8 343 2 1 0.8 4.2 400 43 11.9 201 267 27.8 21.9 21.9 1796 AE 1928 1 1928 0 95 0 48 0 85.5 167.9 289 1 1 0.63 3.8 262 43 11.1 252 219 28.5 22 20.3 2565 DSMB 2849 0 2849 0 96 0 49 0 66.7 165 227 2 1 0.3 4.2 180 40 10 188 177 17.5 20.7 16.2 1936 inconvenience 2302 0 2302 0 97 1 46 0 50.3 158.9 1560 3 1 1.5 4.6 458 205 11.6 289 135 16.4 21 19.5 2951 DSMB 3317 0 3317 0 98 0 27 0 65.9 170.7 279 1 1 0.8 4.2 258 66 12.2 220 219 28.9 20.8 21 553 inconvenience 563 0 563 0 99 1 53 0 52.3 152.7 1984 2 1 0.8 3.7 314 45 11.6 254 185 19 17.9 17.3 2716 DSMB 3146 0 3146 0 100 1 65 0 71.2 152.4 219 3 1 0.3 4.1 72 12 13.1 205 272 15.7 19.3 19.3 608 cancer 2359 0 2359 0 101 0 64 1 87.1 177.2 2303 3 1 0.6 4.1 98 16 11.9 214 323 16 19.5 16.3 2909 DSMB 3283 0 3283 0 102 0 63 0 66.7 164.8 2440 3 1 0.6 3.7 141 53 11.5 256 408 17.8 19.2 19.2 549 cancer 3381 0 3381 0 103 0 48 0 51 165.99 641 2 1 0.8 4.2 74 13 13.5 157 246 20.7 20.8 14.3 1936 DSMB 1946 0 1946 0 104 1 62 0 60.9 153.71 314 3 1 0.2 4.3 164 24 9.5 207 294 14.6 12 11.4 2405 DSMB 2681 0 2681 0 105 1 46 0 87.5 169.4 1256 2 1 1 3.8 394 169 11.1 402 195 28.4 21.4 21.4 2228 AE 3260 1 3371 0 106 0 55 0 76.5 153.4 396 2 1 1.3 3.7 277 25 12.1 293 262 20.3 16.1 13.1 1957 DSMB 2393 0 2393 0 107 1 37 0 83.3 174.79 404 2 1 0.3 4.3 203 27 11.2 189 212 28.7 27.6 23.6 3035 DSMB 3429 0 3429 0 108 0 58 0 109.9 170.2 769 1 1 0.7 3.8 113 9 11.4 221 227 14.6 14.8 14.8 504 AE 561 0 561 0 109 1 62 0 65.5 167.6 1542 4 1 0.4 3 535 40 10.6 259 184 15.3 NA NA 287 AE 564 1 1056 0 110 1 53 0 50.3 151.1 4117 3 1 0.7 3.9 251 70 10.9 228 257 15.7 14.5 14.7 2768 DSMB 3214 0 3214 0 111 1 50 0 76.1 169.69 399 4 1 1.1 3.8 155 35 11.4 140 142 21.7 23.4 22.6 2482 cancer 3142 0 3142 0 112 0 42 0 66.5 167.6 324 2 1 0.3 3.7 238 26 9.4 310 285 16.3 18 15.6 2810 DSMB 3163 0 3163 0 113 1 55 0 55.2 160 2376 1 1 0.6 3.9 250 27 11.9 158 261 23.5 9.1 9.3 2782 death 2782 1 2782 1 114 0 63 0 69.6 160.2 1380 3 1 1.1 3.7 108 32 10.9 174 236 17 16.3 14.3 2572 DSMB 2947 0 2947 0 115 0 46 0 92.3 168.33 439 3 1 0.5 4.1 111 32 10.9 225 271 27.8 18.8 18.5 2940 DSMB 3378 0 3378 0 116 1 45 0 69.1 179.8 242 2 1 0.3 3.7 98 17 11.4 193 193 22.5 20.1 18.2 2925 DSMB 3372 0 3372 0 117 1 50 0 64.6 172.7 605 1 1 0.4 4.2 58 35 12.6 171 176 27.9 21.1 19.8 2422 DSMB 2860 0 2860 0 118 1 46 0 91.2 166.2 1505 4 2 1 3.3 176 56 13.3 175 86 15.2 18.3 17.6 934 AE 1252 1 2652 0 119 0 55 0 48.5 162.7 352 3 1 0.7 4.5 148 19 10.9 227 197 15.6 15.6 12.2 3133 DSMB 3534 0 3534 0 120 1 51 1 95.4 181.1 297 3 1 0.4 4.3 183 78 11.9 274 546 37.7 35.8 34.8 1946 DSMB 2307 0 2307 0 121 1 47 0 58.6 164.7 2286 2 1 2.6 4 504 147 10.5 364 238 21.3 16.4 14.4 2877 DSMB 3305 1 3305 0 122 0 43 0 65.1 167.7 1979 1 1 0.5 3.9 67 17 10.9 232 290 21.4 23.6 19.5 1174 comorbidity 3118 0 3118 0 123 1 60 0 74.5 163.7 491 1 1 0.5 4 224 9 11.7 257 252 23.1 22.7 19.7 1949 DSMB 2398 0 2398 0 124 1 51 0 53.6 159.1 1292 3 2 0.5 3.5 168 66 9.5 223 146 14.2 15.4 13.5 2797 DSMB 369 1 2978 0 125 1 51 0 73.7 161 528 2 1 0.5 3.9 81 25 11 162 294 16 NA NA 248 AE 3052 0 3052 0 126 1 44 0 64.2 169.2 1200 2 1 0.8 3.6 268 171 10.9 260 184 20.1 19 18.1 1703 death 1703 1 1703 1 127 0 39 0 80.1 164.7 1227 3 2 0.6 3.7 531 60 11.5 283 153 17.1 13.8 13.3 1641 comorbidity 2504 1 3349 0 128 0 48 0 54.1 151.2 884 4 1 1.2 3.3 543 141 11.6 260 221 15.7 14.6 14.6 1932 DSMB 2369 0 2369 0 129 0 52 0 59.5 151.7 1126 1 1 0.7 4.3 123 42 11.4 249 234 17.7 16.6 16.6 2044 DSMB 2299 0 2299 0 130 0 48 0 60.1 170.9 1025 2 1 0.8 3.9 213 27 11.9 191 186 18 23.2 17.8 2523 DSMB 2889 0 2889 0 131 1 66 0 64.9 156.9 1833 3 1 0.4 3.7 223 68 10.9 283 234 12.8 8.8 8.8 1495 AE 1307 1 1526 1 132 1 48 0 57.2 167.5 1253 2 1 0.4 4 94 25 13.1 195 167 20 18.6 15.2 2930 DSMB 3331 0 3331 0 133 1 62 1 77.6 180.6 1067 2 1 0.6 3.8 124 30 12.7 161 224 25.4 26.7 25 2268 DSMB 2677 0 2677 0 134 1 45 0 87.3 178.1 442 1 1 0.6 4.4 181 50 12 191 223 27.3 30.8 30.8 3095 DSMB 3492 0 3492 0 135 0 54 0 67.4 168.3 202 1 1 0.5 3.9 106 16 10.9 231 294 21.3 20.9 18.1 2015 DSMB 2450 0 2450 0 136 1 59 1 64.6 170 1959 2 2 0.7 3.9 223 42 11.8 177 125 22.9 21.1 18.5 1634 AE 3396 0 3396 0 137 1 41 0 90.6 172.79 413 3 1 0.4 4.1 244 33 12.2 180 245 27.4 28.9 26.9 2916 DSMB 3357 0 3357 0 138 0 49 0 65.7 152.14 1767 1 1 1.3 3.9 229 28 11.9 196 172 18.9 16.5 15.9 2831 DSMB 3283 0 3283 0 139 0 68 0 56.8 173.5 2358 3 1 0.3 3.8 320 28 12.1 277 334 15.9 13.4 9.9 3162 DSMB 3535 0 3535 0 140 1 49 0 60.6 169.1 382 2 1 0.1 3.6 112 10 12.5 187 425 22.5 22.8 20.1 2812 DSMB 3158 0 3158 0 141 0 50 0 85.2 159.4 631 3 2 2.3 3.8 285 75 13.9 187 209 15.5 15.5 15.5 1098 transplant 1098 1 1098 0 142 1 45 0 83.7 177.16 1145 4 1 0.7 4.2 384 60 12.2 215 372 28.5 22.6 21.4 3130 DSMB 3547 0 3547 0 143 0 53 0 89.4 174.1 719 1 1 0.3 3.7 110 18 10.8 264 191 25 21.9 21.9 2617 DSMB 2919 0 2919 0 144 0 61 0 88.1 155.4 246 2 1 0.6 3.9 84 23 12.3 223 245 16.7 16.4 16.4 2096 inconvenience 2105 0 2105 0 145 1 57 0 71.7 161.1 967 2 1 0.5 4.5 165 50 11.2 310 397 23.1 19 18.3 2349 cancer 1277 1 3057 0 146 0 46 0 94.3 158.11 3941 2 1 0.5 4.1 88 24 11.5 217 270 20 18.9 18.4 2775 DSMB 3137 0 3137 0 147 0 35 0 NA NA 462 1 1 0.7 4.6 254 65 11.3 289 444 17.2 19.2 18 2170 inconvenience 2181 0 2181 0 148 0 45 0 89.7 161.4 1233 2 1 0.7 4 265 48 11.9 274 285 22.5 19.5 16.4 2341 AE 3207 0 3207 0 149 1 49 0 79.5 163.9 2602 3 1 1.2 4.3 135 120 12.3 216 192 21.2 19.6 19.6 2891 DSMB 3289 0 3289 0 150 1 47 0 94.2 167.6 406 2 1 0.4 3.5 147 35 12.8 221 292 20.6 15.6 15.6 1115 inconvenience 1125 0 1125 0 151 0 50 0 70.1 165.4 984 2 1 0.5 4.2 109 43 11.1 309 317 22.9 18.8 16.2 3198 DSMB 3595 0 3595 0 152 0 53 0 65.8 158.3 1471 2 1 0.6 4.2 271 76 11.9 265 408 18.6 16 16 1060 AE 3624 0 3624 0 153 1 49 0 50.4 155.1 1298 3 1 0.2 4.4 213 40 9.6 253 221 14.9 17.7 12.6 3055 DSMB 3485 0 3485 0 154 1 55 0 52 164.41 268 2 1 0.1 3.7 217 47 9.5 213 314 18.8 17.3 17.3 2166 DSMB 2611 0 2611 0 155 0 53 0 48.7 155 2076 3 1 0.9 4.1 430 70 11.1 254 247 13.3 17.4 17.1 766 progression 1258 1 1771 0 156 0 48 0 51 158.9 1512 4 1 0.9 3.9 260 40 13.8 145 121 18.8 16.5 14.3 3110 DSMB 3456 0 3456 0 157 1 58 0 74.9 160 842 2 3 0.7 3.9 375 54 11.1 264 312 26.5 17.9 17.4 2831 DSMB 3221 0 3221 0 158 0 43 0 88.4 172.3 304 3 1 0.8 4.1 261 51 13.9 257 265 29.4 26.7 26.5 570 inconvenience 580 0 580 0 159 1 64 0 62.6 157.9 327 4 1 0.6 3.5 124 40 11.8 164 162 16.1 NA NA 553 AE 1259 1 3012 0 160 1 39 0 97 178.2 600 3 1 0.7 3.9 557 54 12 240 143 26.5 19.9 19.9 2265 DSMB 2669 0 2669 0 161 0 39 0 71 160 228 2 1 1.3 3.8 633 129 11.9 276 222 18.3 13.7 13.7 2119 DSMB 2569 0 2569 0 162 1 51 0 57.4 154.1 203 3 1 1.7 4.3 721 151 10.3 281 370 20.7 22 21.6 1750 DSMB 2171 0 2171 0 163 1 54 0 60.2 151.5 1190 4 1 0.3 4.3 121 40 11 230 241 11.7 12 12 2877 DSMB 3212 0 3212 0 164 1 47 0 65.7 163.4 2047 2 1 0.8 3.9 81 23 10.8 157 191 31.1 29.6 23.8 3167 DSMB 3450 0 3450 0 165 1 54 0 59.1 156.64 2338 3 2 0.5 4.3 264 57 12.1 233 306 NA 10.7 10.7 3131 DSMB 3141 0 3141 0 166 0 45 0 68.7 165.9 2147 2 1 0.3 4.4 105 38 12 267 408 21.2 21.3 21.1 675 comorbidity 685 0 685 0 167 0 54 0 58.2 156.2 611 3 1 1 4.1 165 29 13.3 228 160 18.5 12.2 11.6 2573 DSMB 3008 0 3008 0 168 1 44 0 65.1 168.9 239 4 1 0.5 4 62 23 9.2 184 266 18.6 18 17.8 2069 DSMB 2393 0 2393 0 169 0 46 0 59.4 172.2 488 3 1 0.5 3.6 533 146 11.1 248 160 15.3 15.6 15.4 543 AE 964 1 3122 0 170 0 54 0 61.9 169.5 615 4 1 1.3 3.8 269 64 11.9 287 130 16.5 13.2 13.2 1762 AE 1854 1 2007 1 171 1 40 1 74.3 175.2 594 2 1 0.6 3.9 473 51 11.5 440 263 30.7 NA NA 349 inconvenience 486 1 486 1 172 0 59 0 90.4 155.5 343 3 1 0.8 4 400 61 11.8 262 128 21 16.9 16.3 2002 DSMB 2427 0 2427 0 173 0 40 0 56.4 166.51 777 1 1 0.5 4.5 138 18 11.6 197 261 16.3 18.7 17.3 3111 DSMB 3493 0 3493 0 174 0 65 0 94.4 166.1 2361 4 1 0.6 4 121 29 11.1 189 132 16.4 18.6 16.2 1970 DSMB 2373 0 2373 0 175 0 62 0 57 160.16 1136 4 1 1.1 3.7 267 15 12.4 203 232 13.2 10.2 10 2794 inconvenience 2516 1 3218 0 176 0 67 0 65.6 161.6 5038 1 1 0.8 4.3 115 27 11.5 245 317 22.4 21 20.6 1866 DSMB 2293 0 2293 0 177 1 70 0 60.3 159.02 999 2 1 0.7 4 197 46 12 219 255 19.4 15.2 11.6 3154 DSMB 3535 0 3535 0 178 0 50 0 48.7 157.4 868 3 1 1.6 4.3 1002 252 12.1 371 222 19.7 10.3 10.3 2212 inconvenience 2239 0 2239 0 179 0 49 0 65 165.1 375 3 1 0.1 3.7 280 50 8.8 209 181 11.7 13.1 12.3 2098 inconvenience 2107 0 2107 0 180 0 48 1 103.9 188.46 255 2 1 1.04 4.3 114 39 11.4 179 352 33.7 37.2 32.7 2741 DSMB 3086 0 3086 0 181 1 53 0 67.8 162.6 1498 2 1 0.6 4.4 206 27 11.9 161 619 20.8 15.2 15 3273 DSMB 3625 0 3625 0 182 1 43 0 87.3 164.9 1893 1 1 0.8 3.5 116 28 10.9 256 194 28.6 NA NA 256 AE 288 0 288 0 183 0 54 1 96 186.4 433 4 1 0.9 3.9 209 54 12.4 195 188 41 25.9 25.7 2257 DSMB 2617 0 2617 0 184 0 48 0 65 164.41 5269 3 1 0.1 4.3 120 35 11.3 204 286 17.8 16.8 16.8 2782 DSMB 3199 0 3199 0 185 0 42 1 106 182.41 300 3 1 0.6 4.3 279 35 11.9 NA 295 26.1 28.1 27.3 938 inconvenience 948 0 948 0 186 1 64 0 52.9 159.7 3269 2 1 0.9 4 188 28 12.3 235 236 21.9 18.8 18.8 2250 DSMB 2674 0 2674 0 187 0 56 0 57.8 160.4 728 4 2 1.4 4 312 69 12 246 168 18.4 16 16 1310 cancer 1249 1 1932 1 188 1 44 0 85.1 166.1 407 3 1 0.4 4.6 56 16 11.1 260 315 23.2 22.2 22 740 progression 2545 1 3107 0 189 1 50 0 76.6 157.89 303 4 2 0.5 3.9 119 85 9.9 185 96 18 NA NA 109 AE 144 1 361 0 190 1 46 0 62.7 154.4 203 3 1 0.5 3.6 593 53 9.3 306 173 13.9 14.6 14.8 535 AE 1793 1 1793 1 191 0 49 0 83.2 170.94 1163 1 1 0.5 4.6 279 39 12 227 344 28 24.2 17.3 2948 DSMB 3322 0 3322 0 192 1 45 0 71.7 160.5 879 4 1 0.3 4.2 341 67 9.9 210 213 16.5 18.7 18.9 640 AE 3228 0 3228 0 193 1 55 0 78.2 172.01 2299 2 1 0.2 4.1 502 72 8.4 394 356 18 21.8 17 2124 DSMB 2527 0 2527 0 194 1 33 0 42 152.1 2100 3 1 0.5 4.5 275 102 10.4 306 167 28.7 23 17.5 3188 DSMB 3533 0 3533 0 195 1 53 0 85.5 161.12 398 3 1 0.8 3.7 155 30 13.2 199 237 15.6 14.8 14.6 2769 death 2769 1 2769 1 196 1 41 0 54.79 157.24 1190 3 2 1 3.9 458 83 11.8 329 255 18.7 12.9 12.9 2879 DSMB 3290 0 3290 0 197 0 48 0 83.7 165.3 3402 1 2 1.8 3.2 134 26 12.4 198 94 16.8 16.1 14.7 2394 DSMB 2846 0 2846 0 198 1 56 0 101.6 171.9 355 3 1 0.7 4.1 259 29 11.2 370 199 23.8 14.6 14.4 2461 DSMB 2140 1 2755 1 199 0 62 0 76.6 172.39 273 4 1 0.5 4.2 119 47 11 174 158 15.1 10.5 10.7 1200 AE 2548 0 2548 0 200 0 58 0 76.4 167.8 583 1 1 0.5 3.5 182 14 10.9 235 275 22.4 17.9 17.9 2913 AE 3337 0 3337 0 201 0 43 0 50.7 151 637 2 1 0.9 4 1133 308 11.2 382 561 13.4 8.7 8.5 2732 DSMB 2806 0 2806 0 202 1 65 1 77.1 176.7 311 1 1 0.3 3.8 177 19 14.4 281 357 19.3 14.7 14.7 590 cancer 1059 1 1059 1 203 1 37 0 61.9 149 244 1 1 0.6 4.3 91 26 11.7 248 288 17.8 14.7 14.3 2306 DSMB 2465 0 2465 0 204 1 46 0 64.2 165.61 202 3 1 0.1 4 111 27 10.2 178 270 20.3 21.3 19.7 2692 DSMB 3094 0 3094 0 205 1 54 0 62.6 161.9 225 2 1 0.2 4.1 301 181 8.3 231 425 13.2 14.8 14 1957 DSMB 2385 0 2385 0 206 0 56 0 74 179.81 2060 3 1 0.8 4.2 471 38 11.9 164 99 16 31.9 14.3 1010 AE 3393 0 3393 0 207 1 45 0 76.3 169.4 247 3 1 0.6 4.2 242 57 11.7 271 222 21.9 19.2 18.8 2876 DSMB 1841 1 3212 0 208 1 42 0 42.3 155.5 337 3 1 0.1 4.1 126 18 9.7 176 303 19.1 18.3 15.3 2586 DSMB 2946 0 2946 0 209 0 48 0 50.8 165.3 398 1 1 0.7 3.9 151 72 12.1 155 273 19.6 15.1 12.6 3104 DSMB 3541 0 3541 0 210 0 53 1 100.9 193.7 2344 2 1 0.9 4.2 268 132 9.9 295 166 40 39.4 32.1 2574 DSMB 2875 0 2875 0 211 0 60 0 72.4 160.8 1501 2 1 0.7 4.4 194 41 11.1 326 294 18.4 16.7 16.7 2317 cancer 2960 0 2960 0 212 1 51 0 94.7 178.8 1261 3 1 0.7 4.1 168 34 11.7 216 210 25.8 25 22.3 3157 DSMB 3617 0 3617 0 213 1 44 0 69.7 157.8 364 2 1 0.6 4.5 110 51 10.6 260 337 21.6 21.8 21 2203 DSMB 2595 0 2595 0 214 0 61 0 63.8 158.2 1374 2 2 0.7 4.8 145 33 11.7 227 259 18.5 16.1 16.3 2664 DSMB 3101 0 3101 0 215 0 36 0 80.5 170.79 247 2 1 0.6 4.4 146 16 10.4 236 408 21.3 27 19.8 2962 DSMB 3360 0 3360 0 216 0 52 0 79.2 165.2 1680 3 1 1.2 4.5 104 41 10.5 217 195 18 20 17.2 2006 DSMB 2448 0 2448 0 217 1 54 0 77.7 165.01 1940 4 1 0.8 3.7 259 56 9.4 356 200 15.8 NA NA 507 AE 696 1 1006 0 218 1 40 0 64.1 148.1 247 3 1 0.6 3.9 239 28 9.1 173 223 17.3 21.3 17.4 2621 DSMB 3031 0 3031 0 219 1 48 0 57.7 155 1668 3 1 0.2 3.9 116 60 11.1 199 245 16.4 15.3 11.9 2818 DSMB 3220 0 3220 0 220 0 38 0 65.8 149.5 284 1 1 0.2 4 96 21 11.1 215 392 21.3 18.5 18.5 2874 DSMB 3213 0 3213 0 221 0 54 1 86.3 166.1 2428 4 1 1 4.1 273 74 11.9 304 159 20.2 NA NA 72 progression 72 1 98 0 222 1 42 0 76.8 158.9 722 3 1 0.4 4.4 227 NA 11.6 NA 225 25.3 17.7 17.7 2180 DSMB 2622 0 2622 0 223 1 67 0 64.5 170.8 6552 4 1 0.6 3.9 154 28 11.1 232 129 17 9.5 7.8 2680 DSMB 2817 1 2817 1 224 1 52 0 67.1 161.3 1072 3 1 1.4 3.6 168 111 12.9 168 91 20 NA NA 305 progression 78 1 547 0 225 1 61 0 51.7 169.78 791 2 1 0.2 4 98 17 12.6 248 298 16.1 NA NA 45 inconvenience 104 0 104 0 226 0 64 0 46.4 150.4 3389 3 1 0.4 3.7 267 44 9.7 197 110 13.5 12 12 2046 cancer 2006 1 2681 0 227 0 58 0 61.1 161.6 2997 3 2 1.2 4.5 325 94 11.9 209 132 18.6 12.1 12.1 2049 transplant 202 1 2059 0 228 0 61 0 56.6 155.8 4470 3 1 0.2 4.2 226 41 11.6 NA 139 14.9 14.5 14.1 2435 DSMB 2799 0 2799 0 229 0 52 0 79.9 158.9 336 4 1 0.8 3.5 203 32 12 143 165 16.3 NA NA 81 AE 92 0 92 0 230 1 52 0 73.6 161.4 1288 2 1 1.3 3.6 369 132 8.8 285 210 12.4 14.1 11.9 2754 DSMB 3198 0 3198 0 231 0 52 0 80.1 151.9 298 3 1 0.6 4.2 145 42 12.3 271 234 17.6 16.8 15.5 1783 DSMB 2235 0 2235 0 232 1 41 0 65.3 160.3 253 3 1 0.9 4.4 440 100 12.2 247 346 20.7 21.7 19.3 2593 DSMB 2987 0 2987 0 233 1 33 0 55.7 165.1 320 2 1 0.8 4.4 566 152 12.9 277 176 26.8 24.4 22.6 1704 DSMB 2052 0 2052 0 234 0 35 0 77.9 159 338 2 1 0.9 4.2 69 49 9.5 195 307 22.6 25.8 20.7 2166 DSMB 2562 0 2562 0 235 0 59 0 67.4 168.3 4647 2 1 0.8 4.5 336 44 12.2 239 263 16.2 NA NA 605 comorbidity 2373 0 2373 0 236 0 62 0 62.3 162.1 3213 2 1 0.5 3.8 383 37 9.3 324 331 17 20.2 16.4 1964 DSMB 2350 0 2350 0 237 0 64 0 84.7 165.84 3019 2 1 0.4 4.3 173 85 11 262 255 24.5 18.3 18.3 1724 inconvenience 1734 0 1734 0 238 1 45 0 87.2 158.9 2899 4 1 0.7 4.5 309 43 11.1 210 307 23.5 15.8 15.4 3064 DSMB 2821 1 3444 0 239 0 64 1 79.1 180 3884 3 1 1.2 4.7 647 58 12 267 217 27.1 26 17.8 1837 DSMB 2245 0 2245 0 240 0 60 0 44.9 146.4 817 2 1 0.5 3.8 264 39 11.1 200 161 15.7 12.5 12.7 3211 DSMB 3618 0 3618 0 241 1 66 0 69.3 154.74 1625 3 1 0.3 3.7 155 20 11.1 214 244 15.6 12.6 10 3081 DSMB 3470 0 3470 0 242 1 57 1 65.2 165.74 1912 3 1 0.9 4.3 155 27 12.5 213 136 26.3 14.9 14.8 3108 DSMB 3456 0 3456 0 243 1 56 0 49.2 154.8 3127 2 1 0.7 3.6 272 70 10.9 170 349 13.4 15.4 10.2 3183 DSMB 3575 0 3575 0 244 0 55 0 63.3 160.2 1927 2 1 1 4 207 NA 11.9 213 266 18.8 11.6 11.6 2995 DSMB 3410 0 3410 0 245 1 46 0 75 168.6 1518 3 1 0.4 3.7 207 25 9.4 234 217 19.1 19.6 17 3118 DSMB 3513 0 3513 0 246 1 44 0 56.7 160.4 594 1 1 0.3 4 215 33 11 229 273 19.2 NA NA 324 inconvenience 2891 0 2891 0 247 1 57 0 76.1 164.3 719 1 1 0.7 3.7 66 16 11.3 200 187 18.8 18.9 18.7 2441 inconvenience 2451 0 2451 0 248 1 57 0 113.3 158.36 1289 1 1 0.7 4.1 196 28 12.8 267 338 25 15.4 15.2 2498 AE 3440 0 3440 0 249 0 42 0 77.1 172.4 830 4 2 1.7 3.3 232 55 13.1 186 101 20.5 19.2 15.4 2929 DSMB 2588 1 3379 0 250 0 65 0 74.9 166 877 1 1 1 4 104 28 11.9 244 191 24.2 17.9 17.7 899 AE 1085 0 1085 0 251 0 66 0 69 151.1 858 4 1 0.4 4 132 34 11.7 208 244 14.7 10 8.6 3121 DSMB 3560 0 3560 0 252 1 60 0 50.9 158.01 239 4 1 1.7 4 437 183 11.6 314 187 18.7 17.6 17.6 521 cancer 928 1 1468 0 253 1 57 0 66.8 159.6 4894 3 1 0.4 4 112 27 11.3 263 172 8.9 11.2 9.9 3127 DSMB 3446 0 3446 0 254 1 65 0 77.4 170.4 5424 3 1 0.7 4.1 244 37 10.8 248 179 19.8 21.3 18.9 2198 DSMB 1349 1 2518 0 255 1 38 0 67.2 153.99 1070 2 1 0.3 4 124 27 9.8 252 316 12.1 18.9 12.1 2376 DSMB 2820 0 2820 0 256 0 48 0 83.3 178.4 331 2 1 0.5 4.1 140 32 9.7 204 345 21 27.2 24 2537 DSMB 2911 0 2911 0 257 0 56 0 74.3 150.5 715 1 1 1.2 4.5 103 30 10.9 336 235 23.5 17 16.9 2965 DSMB 3309 0 3309 0 258 1 35 0 63.2 175.5 1281 3 1 0.9 3.6 156 53 11.9 213 181 26.4 30.1 15.2 3128 DSMB 3445 0 3445 0 259 0 68 0 71.9 158.3 1470 3 2 0.6 4.3 197 27 10.9 179 116 21 21 14.1 2208 AE 2419 1 2419 1 260 1 55 1 72.8 179.7 1268 4 2 0.6 4.1 190 70 11.7 234 129 27.5 26.8 24.9 1660 inconvenience 1671 0 1671 0 261 0 52 0 76.6 162.5 2955 3 2 1.1 4.2 514 38 11.2 294 290 12.5 19.6 15.5 2870 DSMB 3254 0 3254 0 262 0 61 0 54.3 154.2 867 3 1 0.4 4.3 329 32 11.6 181 185 15.1 18.4 14.4 2891 DSMB 3289 0 3289 0 263 1 48 0 57.7 159.5 242 2 1 0.43 3.8 118 37 12.1 203 167 19.8 NA NA 368 cancer 3085 0 3085 0 264 0 52 0 47.1 162.2 2027 3 1 1.1 4.1 445 126 10.3 372 156 19.1 20.6 19 1955 DSMB 2337 0 2337 0 265 1 47 0 51 153.9 4780 2 1 1.1 4.2 390 70 10.9 248 189 24.9 19.3 18.4 1902 inconvenience 1902 1 3610 0