**Scott S. Emerson, M.D., Ph.D.**

Professor of Biostatistics

Department of Biostatistics

University of Washington

**Biost 517: Applied Biostatistics I** (taught jointly with **Biost 514: Biostatistics I**)

Introduction to the analysis of biomedical data. Descriptive and inferential statistical analysis for discrete, continuous,

and right censored random variables. Analytic methods based on elementary parametric and non-parametric models

for one sample; two sample (independent and paired), stratified sample, and simple regression
problems.

Instructor: | Scott S. Emerson, M.D., Ph.D. |
Navneet Hakhu nhakhu@uw.edu Linbo Wang lbwang@uw.edu |

Office: | HSB F673 | |

Phone: | 616-6678(Biostatistics) | |

Email: | semerson@uw.edu | |

Office Hours: | Tu 3:00pm - 5:00pm (or by appointment) |

**Times and Places**

Lectures : MWF 9:30am - 10:20am HSD 209

Disc AA : M 8:30am - 9:20am HST 473

Disc AC : Tu 8:30am - 9:20am HST 635

Disc AB : W 8:30am - 9:20am HST 473

Disc AA : F 8:30am - 9:20am HST 359

**Syllabus and General Information**

BIOST 517 Syllabus (pdf)

**Information and Tutorials on Stata**

Ordering Stata IC through Grad Plan

Prof. Jim Hughes’ Stata tutorials (requires UWnet ID)

**R Materials**

Functions for descriptive statistics (revised 20121025)
R source code
Help files

Functions for one sample inference (revised 20121110)
R source code
Help files

Functions for regression (revised 20121206)
R source code
Help files

Tutorial re HW #4 R code

**Supplemental Materials**

Approach to analyzing a data set (pdf)

Use of Logarithmic Transformations (pdf)

**Course Materials**

Day | Date | Handouts | Videos | HW Assigned | HW Due | Miscellaneous |
---|---|---|---|---|---|---|

Mon | Sep 24 | Lecture 1 | Lecture Discussion | HW #1 (Keys: Key Stata Excel ) | ||

Wed | Sep 26 | Lecture 2 | Lecture | |||

Fri | Sep 28 | Lecture 3 | Lecture Discussion | |||

Mon | Oct 1 | Lecture | ||||

Wed | Oct 3 | Lecture 4 | Lecture | HW #2 (Keys: Key ) | HW #1 | |

Fri | Oct 5 | Quiz | Lecture | Quiz | HW: Video | |

Mon | Oct 8 | Lecture 5 | Lecture | |||

Wed | Oct 10 | Lecture 6 | (No video) | HW #2 | ||

Fri | Oct 12 | Lecture | HW #3 (Keys: Key Stata Excel ) | |||

Mon | Oct 15 | Lecture | ||||

Wed | Oct 17 | Lecture 7 | Lecture | |||

Fri | Oct 19 | Lecture | HW #4 (Keys: Key Stata Excel ) | HW #3 | ||

Mon | Oct 22 | Lecture | ||||

Wed | Oct 24 | Lecture 8 | (No video) | |||

Fri | Oct 26 | Quiz | Lecture | HW #4; Quiz | HW: Video Handout | |

Mon | Oct 29 | Lecture | HW #5 (Keys: Key Stata ) | |||

Wed | Oct 31 | Lecture 9 | Lecture | |||

Fri | Nov 2 | Lecture 10 | Lecture | HW #5 | Review (HST 747 3 - 5pm) | |

Mon | Nov 5 | Midterm | Midterm | Midterm | ||

Wed | Nov 7 | Lecture 11 | Lecture | HW #6 (Keys: ) | ||

Fri | Nov 9 | Lecture | ||||

Mon | Nov 12 | (Holiday) | ||||

Wed | Nov 14 | Lecture | HW #6 | |||

Fri | Nov 16 | Lecture 12 (rev) | Lecture | Project | ||

Mon | Nov 19 | Lecture | HW #7 (Keys: ) | |||

Wed | Nov 21 | Lecture 12 (rev) | Lecture | |||

Fri | Nov 23 | (Holiday) | ||||

Mon | Nov 26 | Lecture 13 | Lecture | |||

Wed | Nov 28 | Lecture 14 | Lecture Discussion | HW #7; Project SAP | Proj Disc: DFMO Leukemia | |

Fri | Nov 30 | Lecture | HW #8 (Keys: Key ) | |||

Mon | Dec 3 | Lecture 15 | Lecture | |||

Tue | Dec 4 | Project Draft | ||||

Wed | Dec 5 | Lecture | Ref Rpt Examples 1 2 3 | |||

Thu | Dec 4 | Referee Report | ||||

Fri | Dec 7 | Lecture | HW #8 | |||

Wed | Dec 12 | Final Exam | Final Project |

**Datasets**

Dataset | Documentation | Data |
---|---|---|

Adult FEV | adultfev.doc | adultfev.txt |

Audiology | audio.doc | audio.csv |

Beta carotene (summarized) | carot.doc | carot.txt |

Detailed Beta carotene | bcarot.doc | bcarot.txt |

DSST (cognitive function test) | dsst.doc | dsst.txt |

Chemosensitizers in Chemotherapy | chemo.doc | chemo.txt |

DFMO | dfmo.doc | dfmowide.txt, dfmolong.txt |

FEV and Smoking in Children | fev.doc | fev.txt |

Biomarkers of Inflammation | inflamm.doc | inflamm.txt |

Clinical Trial Idarubicin in AML | leukemia.doc | leukemia.txt |

Mayo Clinic PBC | liver.doc | liver.txt |

MRI and Cerebral Atrophy | mri.pdf | mri.txt |

PBC Trial Laboratory | mtxlabs.doc | mtxlabs.txt |

PBC Trial Outcomes | mtxotcm.doc | mtxotcm.txt |

Clinical Trial in Non-Small Cell Lung Cancer | nsclc.doc | nsclc.txt |

Screening Data For PBC | pbcscreen.doc | pbcscreen.txt |

PSA | PSA.doc | psa.txt |

Salary | salary.doc, initsalary.doc | salary.txt |

SEP | SEP.doc | sep.txt |